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Different evolutionary patterns of hypoxia-inducible factor α (HIF-α) isoforms in the basal branches of Actinopterygii and Sarcopterygii()

Hypoxia-inducible factor (HIF) is a crucial regulator of cellular and systemic responses to low oxygen levels. Here we firstly cloned three HIF-α isoforms from the basal branches of Osteichthyes and used computational tools to characterise the molecular change underlying the functional divergence of...

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Detalles Bibliográficos
Autores principales: Chi, Wei, Gan, Xiaoni, Xiao, Wuhan, Wang, Wen, He, Shunping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836196/
https://www.ncbi.nlm.nih.gov/pubmed/24265980
http://dx.doi.org/10.1016/j.fob.2013.09.004