Mathematical Modeling of Oncogenesis Control in Mature T-Cell Populations

T-cell receptor (TCR) polyclonal mature T cells are surprisingly resistant to oncogenic transformation after retroviral insertion of T-cell oncogenes. In a mouse model, it has been shown that mature T-cell lymphoma/leukemia (MTCLL) is not induced upon transplantation of mature, TCR polyclonal wild-t...

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Detalles Bibliográficos
Autores principales: Gerdes, Sebastian, Newrzela, Sebastian, Glauche, Ingmar, von Laer, Dorothee, Hansmann, Martin-Leo, Roeder, Ingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836208/
https://www.ncbi.nlm.nih.gov/pubmed/24409176
http://dx.doi.org/10.3389/fimmu.2013.00380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836208/
https://www.ncbi.nlm.nih.gov/pubmed/24409176
http://dx.doi.org/10.3389/fimmu.2013.00380

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