Mechano-transduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer associated fibroblasts

To learn more about cancer-associated fibroblasts (CAFs), we have isolated fibroblasts from different stages of breast cancer progression and analysed their function and gene expression. These analyses reveal that activation of the YAP transcription factor is a signature feature of CAFs. YAP functio...

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Detalles Bibliográficos
Autores principales: Calvo, Fernando, Ege, Nil, Grande-Garcia, Araceli, Hooper, Steven, Jenkins, Robert P., Chaudhry, Shahid I., Harrington, Kevin, Williamson, Peter, Moeendarbary, Emad, Charras, Guillaume, Sahai, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836234/
https://www.ncbi.nlm.nih.gov/pubmed/23708000
http://dx.doi.org/10.1038/ncb2756

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836234/
https://www.ncbi.nlm.nih.gov/pubmed/23708000
http://dx.doi.org/10.1038/ncb2756

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