miRNAs confer phenotypic robustness to gene networks by suppressing biological noise

miRNAs are small non-coding RNAs able to modulate target-gene expression. It has been postulated that miRNAs confer robustness to biological processes, but a clear experimental evidence is still missing. Using a synthetic biology approach, we demonstrate that microRNAs provide phenotypic robustness...

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Detalles Bibliográficos
Autores principales: Siciliano, Velia, Garzilli, Immacolata, Fracassi, Chiara, Criscuolo, Stefania, Ventre, Simona, di Bernardo, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836244/
https://www.ncbi.nlm.nih.gov/pubmed/24077216
http://dx.doi.org/10.1038/ncomms3364

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836244/
https://www.ncbi.nlm.nih.gov/pubmed/24077216
http://dx.doi.org/10.1038/ncomms3364

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