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The Nrf2-inducers tanshinone I and dihydrotanshinone protect human skin cells and reconstructed human skin against solar simulated UV()

Exposure to solar ultraviolet (UV) radiation is a causative factor in skin photocarcinogenesis and photoaging, and an urgent need exists for improved strategies for skin photoprotection. The redox-sensitive transcription factor Nrf2 (nuclear factor-E2-related factor 2), a master regulator of the cel...

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Detalles Bibliográficos
Autores principales: Tao, Shasha, Justiniano, Rebecca, Zhang, Donna D., Wondrak, Georg T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836278/
https://www.ncbi.nlm.nih.gov/pubmed/24273736
http://dx.doi.org/10.1016/j.redox.2013.10.004