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Effects of PARP-1 Deficiency on Th1 and Th2 Cell Differentiation

T cell differentiation to effector Th cells such as Th1 and Th2 requires the integration of multiple synergic and antagonist signals. Poly(ADP-ribosy)lation is a posttranslational modification of proteins catalyzed by Poly(ADP-ribose) polymerases (PARPs). Recently, many reports showed that PARP-1, t...

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Detalles Bibliográficos
Autores principales: Sambucci, M., Laudisi, F., Novelli, F., Bennici, E., Rosado, M. M., Pioli, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836382/
https://www.ncbi.nlm.nih.gov/pubmed/24319363
http://dx.doi.org/10.1155/2013/375024