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A single amino acid in the F(2) subunit of respiratory syncytial virus fusion protein alters growth and fusogenicity

Respiratory syncytial virus (RSV) causes severe lower respiratory tract infection in children, especially in infants less than 1 year of age. There are currently no licensed vaccines against RSV. rA2ΔM2-2 is a promising live-attenuated vaccine candidate that is currently being evaluated in the clini...

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Detalles Bibliográficos
Autores principales: Lawlor, Heather A., Schickli, Jeanne H., Tang, Roderick S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for General Microbiology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836501/
https://www.ncbi.nlm.nih.gov/pubmed/24092758
http://dx.doi.org/10.1099/vir.0.055368-0