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Niclosamide suppresses Hepatoma cell proliferation via the Wnt pathway

BACKGROUND: The Wnt pathway plays an important role in Hepatocarcinogenesis. We analyzed the association of the Wnt pathway with the proliferation of hepatoma cells using Wnt3a and niclosamide, a drug used to treat tapeworm infection. METHODS: We performed an MTS assay to determine whether Wnt3a sti...

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Detalles Bibliográficos
Autores principales: Tomizawa, Minoru, Shinozaki, Fuminobu, Motoyoshi, Yasufumi, Sugiyama, Takao, Yamamoto, Shigenori, Sueishi, Makoto, Yoshida, Takanobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836661/
https://www.ncbi.nlm.nih.gov/pubmed/24273411
http://dx.doi.org/10.2147/OTT.S50065