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New Antimalarial Hits from Dacryodes edulis (Burseraceae) - Part I: Isolation, In Vitro Activity, In Silico “drug-likeness” and Pharmacokinetic Profiles

The aims of the present study were to identify the compounds responsible for the anti-malarial activity of Dacryoedes edulis (Burseraceae) and to investigate their suitability as leads for the treatment of drug resistant malaria. Five compounds were isolated from ethyl acetate and hexane extracts of...

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Detalles Bibliográficos
Autores principales: Zofou, Denis, Tematio, Esther Laure, Ntie-Kang, Fidele, Tene, Mathieu, Ngemenya, Moses N., Tane, Pierre, Titanji, Vincent P. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836662/
https://www.ncbi.nlm.nih.gov/pubmed/24282507
http://dx.doi.org/10.1371/journal.pone.0079544