Cargando…

Deletion of an X-Inactivation Boundary Disrupts Adjacent Gene Silencing

In mammalian females, genes on one X are largely silenced by X-chromosome inactivation (XCI), although some “escape” XCI and are expressed from both Xs. Escapees can closely juxtapose X-inactivated genes and provide a tractable model for assessing boundary function at epigenetically regulated loci....

Descripción completa

Detalles Bibliográficos
Autores principales: Horvath, Lindsay M., Li, Nan, Carrel, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836711/
https://www.ncbi.nlm.nih.gov/pubmed/24278033
http://dx.doi.org/10.1371/journal.pgen.1003952