Cargando…
Deletion of an X-Inactivation Boundary Disrupts Adjacent Gene Silencing
In mammalian females, genes on one X are largely silenced by X-chromosome inactivation (XCI), although some “escape” XCI and are expressed from both Xs. Escapees can closely juxtapose X-inactivated genes and provide a tractable model for assessing boundary function at epigenetically regulated loci....
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836711/ https://www.ncbi.nlm.nih.gov/pubmed/24278033 http://dx.doi.org/10.1371/journal.pgen.1003952 |