Cargando…

A Small Molecule Glycosaminoglycan Mimetic Blocks Plasmodium Invasion of the Mosquito Midgut

Malaria transmission-blocking (T-B) interventions are essential for malaria elimination. Small molecules that inhibit the Plasmodium ookinete-to-oocyst transition in the midgut of Anopheles mosquitoes, thereby blocking sporogony, represent one approach to achieving this goal. Chondroitin sulfate gly...

Descripción completa

Detalles Bibliográficos
Autores principales: Mathias, Derrick K., Pastrana-Mena, Rebecca, Ranucci, Elisabetta, Tao, Dingyin, Ferruti, Paolo, Ortega, Corrie, Staples, Gregory O., Zaia, Joseph, Takashima, Eizo, Tsuboi, Takafumi, Borg, Natalie A., Verotta, Luisella, Dinglasan, Rhoel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836724/
https://www.ncbi.nlm.nih.gov/pubmed/24278017
http://dx.doi.org/10.1371/journal.ppat.1003757