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Defining the Range of Pathogens Susceptible to Ifitm3 Restriction Using a Knockout Mouse Model
The interferon-inducible transmembrane (IFITM) family of proteins has been shown to restrict a broad range of viruses in vitro and in vivo by halting progress through the late endosomal pathway. Further, single nucleotide polymorphisms (SNPs) in its sequence have been linked with risk of developing...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836756/ https://www.ncbi.nlm.nih.gov/pubmed/24278312 http://dx.doi.org/10.1371/journal.pone.0080723 |