Defining the Range of Pathogens Susceptible to Ifitm3 Restriction Using a Knockout Mouse Model

The interferon-inducible transmembrane (IFITM) family of proteins has been shown to restrict a broad range of viruses in vitro and in vivo by halting progress through the late endosomal pathway. Further, single nucleotide polymorphisms (SNPs) in its sequence have been linked with risk of developing...

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Detalles Bibliográficos
Autores principales: Everitt, Aaron R., Clare, Simon, McDonald, Jacqueline U., Kane, Leanne, Harcourt, Katherine, Ahras, Malika, Lall, Amar, Hale, Christine, Rodgers, Angela, Young, Douglas B., Haque, Ashraful, Billker, Oliver, Tregoning, John S., Dougan, Gordon, Kellam, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836756/
https://www.ncbi.nlm.nih.gov/pubmed/24278312
http://dx.doi.org/10.1371/journal.pone.0080723

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