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Critical Role of Regulator G-Protein Signaling 10 (RGS10) in Modulating Macrophage M1/M2 Activation

Regulator of G protein signaling 10 (RGS10), a GTPase accelerating protein (GAP) for G alpha subunits, is a negative regulator of NF-κB in microglia. Here, we investigated the role of RGS10 in macrophages, a closely related myeloid-derived cell type. Features of classical versus alternative activati...

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Detalles Bibliográficos
Autores principales: Lee, Jae-Kyung, Chung, Jaegwon, Kannarkat, George T., Tansey, Malú G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836764/
https://www.ncbi.nlm.nih.gov/pubmed/24278459
http://dx.doi.org/10.1371/journal.pone.0081785