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Critical Role of Regulator G-Protein Signaling 10 (RGS10) in Modulating Macrophage M1/M2 Activation
Regulator of G protein signaling 10 (RGS10), a GTPase accelerating protein (GAP) for G alpha subunits, is a negative regulator of NF-κB in microglia. Here, we investigated the role of RGS10 in macrophages, a closely related myeloid-derived cell type. Features of classical versus alternative activati...
Autores principales: | Lee, Jae-Kyung, Chung, Jaegwon, Kannarkat, George T., Tansey, Malú G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836764/ https://www.ncbi.nlm.nih.gov/pubmed/24278459 http://dx.doi.org/10.1371/journal.pone.0081785 |
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