Role of Cross-Cleft Contacts in NMDA Receptor Gating

In response to brief glutamate exposure, NMDA receptors produce excitatory currents that have sub-maximal amplitudes and characteristically slow kinetics. The activation sequence starts when glutamate binds to residues located on the upper lobe of extracellularly located ligand-binding domains (LBDs...

Descripción completa

Detalles Bibliográficos
Autores principales: Paganelli, Meaghan A., Kussius, Cassandra L., Popescu, Gabriela K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836766/
https://www.ncbi.nlm.nih.gov/pubmed/24278352
http://dx.doi.org/10.1371/journal.pone.0080953

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836766/
https://www.ncbi.nlm.nih.gov/pubmed/24278352
http://dx.doi.org/10.1371/journal.pone.0080953

Ejemplares similares