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PARP-1 Inhibitor, DPQ, Attenuates LPS-Induced Acute Lung Injury through Inhibiting NF-κB-Mediated Inflammatory Response

Acute lung injury (ALI) is characterized by overwhelming lung inflammation and anti-inflammation treatment is proposed to be a therapeutic strategy for ALI. Poly (ADP-ribose) polymerase-1 has been demonstrated to be involved in tissue inflammation and one of its inhibitors, 3, 4-Dihydro-5[4-(1-piper...

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Detalles Bibliográficos
Autores principales: Wang, Gang, Huang, Xiaojia, Li, Yongjin, Guo, Kangkang, Ning, Pengbo, Zhang, Yanming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836796/
https://www.ncbi.nlm.nih.gov/pubmed/24278171
http://dx.doi.org/10.1371/journal.pone.0079757