Affinity Purification of Human Factor H on Polypeptides Derived from Streptococcal M Protein: Enrichment of the Y402 Variant

Recent studies indicate that defective activity of complement factor H (FH) is associated with several human diseases, suggesting that pure FH may be used for therapy. Here, we describe a simple method to isolate human FH, based on the specific interaction between FH and the hypervariable region (HV...

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Detalles Bibliográficos
Autores principales: Nilsson, O. Rickard, Lannergård, Jonas, Morgan, B. Paul, Lindahl, Gunnar, Gustafsson, Mattias C. U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836803/
https://www.ncbi.nlm.nih.gov/pubmed/24278416
http://dx.doi.org/10.1371/journal.pone.0081303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836803/
https://www.ncbi.nlm.nih.gov/pubmed/24278416
http://dx.doi.org/10.1371/journal.pone.0081303

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