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Canine Notochordal Cell-Secreted Factors Protect Murine and Human Nucleus Pulposus Cells from Apoptosis by Inhibition of Activated Caspase-9 and Caspase-3/7

Introduction Effective therapies that may stop or even reverse disc degeneration remain elusive. A minimally invasive method through which nucleus pulposus (NP) cell viability could be achieved would revolutionize the treatment of degenerative disc disease (DDD). With the presented work, we have inv...

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Detalles Bibliográficos
Autores principales: Mehrkens, Arne, Karim, M. Zia, Kim, Sarah, Hilario, Raychel, Fehlings, Michael G., Erwin, William Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836881/
https://www.ncbi.nlm.nih.gov/pubmed/24436715
http://dx.doi.org/10.1055/s-0033-1357363