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Differential Effects of β-catenin and NF-κB Interplay in the Regulation of Cell Proliferation, Inflammation and Tumorigenesis in Response to Bacterial Infection

Both β-catenin and NF-κB have been implicated in our laboratory as candidate factors in driving proliferation in an in vivo model of Citrobacter rodentium (CR)-induced colonic crypt hyper-proliferation and hyperplasia. Herein, we test the hypothesis that β-catenin and not necessarily NF-κB regulates...

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Detalles Bibliográficos
Autores principales: Chandrakesan, Parthasarathy, Jakkula, Laxmi Uma Maheswar Rao, Ahmed, Ishfaq, Roy, Badal, Anant, Shrikant, Umar, Shahid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836902/
https://www.ncbi.nlm.nih.gov/pubmed/24278135
http://dx.doi.org/10.1371/journal.pone.0079432