Harnessing Gene Conversion in Chicken B Cells to Create a Human Antibody Sequence Repertoire

Transgenic chickens expressing human sequence antibodies would be a powerful tool to access human targets and epitopes that have been intractable in mammalian hosts because of tolerance to conserved proteins. To foster the development of the chicken platform, it is beneficial to validate transgene c...

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Detalles Bibliográficos
Autores principales: Schusser, Benjamin, Yi, Henry, Collarini, Ellen J., Izquierdo, Shelley Mettler, Harriman, William D., Etches, Robert J., Leighton, Philip A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837002/
https://www.ncbi.nlm.nih.gov/pubmed/24278246
http://dx.doi.org/10.1371/journal.pone.0080108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837002/
https://www.ncbi.nlm.nih.gov/pubmed/24278246
http://dx.doi.org/10.1371/journal.pone.0080108

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