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Harnessing Gene Conversion in Chicken B Cells to Create a Human Antibody Sequence Repertoire
Transgenic chickens expressing human sequence antibodies would be a powerful tool to access human targets and epitopes that have been intractable in mammalian hosts because of tolerance to conserved proteins. To foster the development of the chicken platform, it is beneficial to validate transgene c...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837002/ https://www.ncbi.nlm.nih.gov/pubmed/24278246 http://dx.doi.org/10.1371/journal.pone.0080108 |