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Simple Sequence Repeats Together with Mismatch Repair Deficiency Can Bias Mutagenic Pathways in Pseudomonas aeruginosa during Chronic Lung Infection

Pseudomonas aeruginosa is an opportunistic pathogen that chronically infects the airways of cystic fibrosis (CF) patients and undergoes a process of genetic adaptation based on mutagenesis. We evaluated the role of mononucleotide G:C and A:T simple sequence repeats (SSRs) in this adaptive process. A...

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Detalles Bibliográficos
Autores principales: Moyano, Alejandro J., Feliziani, Sofía, Di Rienzo, Julio A., Smania, Andrea M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837008/
https://www.ncbi.nlm.nih.gov/pubmed/24278287
http://dx.doi.org/10.1371/journal.pone.0080514