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Specific Serotonergic Denervation Affects tau Pathology and Cognition without Altering Senile Plaques Deposition in APP/PS1 Mice

Senile plaques and neurofibrillary tangles are major neuropathological features of Alzheimer's Disease (AD), however neuronal loss is the alteration that best correlates with cognitive impairment in AD patients. Underlying neurotoxic mechanisms are not completely understood although specific ne...

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Detalles Bibliográficos
Autores principales: Ramos-Rodriguez, Juan Jose, Molina-Gil, Sara, Rey-Brea, Raquel, Berrocoso, Esther, Garcia-Alloza, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837012/
https://www.ncbi.nlm.nih.gov/pubmed/24278223
http://dx.doi.org/10.1371/journal.pone.0079947