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Identification of an Intrinsic Determinant Critical for Maspin Subcellular Localization and Function

Maspin, a multifaceted tumor suppressor, belongs to the serine protease inhibitor superfamily, but only inhibits serine protease-like enzymes such as histone deacetylase 1 (HDAC1). Maspin is specifically expressed in epithelial cells and it is differentially regulated during tumor progression. A new...

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Detalles Bibliográficos
Autores principales: Dzinic, Sijana H., Kaplun, Alexander, Li, Xiaohua, Bernardo, Margarida, Meng, Yonghong, Dean, Ivory, Krass, David, Stemmer, Paul, Shin, Namhee, Lonardo, Fulvio, Sheng, Shijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837015/
https://www.ncbi.nlm.nih.gov/pubmed/24278104
http://dx.doi.org/10.1371/journal.pone.0074502