Lactate-Induced Release of GABA in the Ventromedial Hypothalamus Contributes to Counterregulatory Failure in Recurrent Hypoglycemia and Diabetes

Suppression of GABAergic neurotransmission in the ventromedial hypothalamus (VMH) is crucial for full activation of counterregulatory responses to hypoglycemia, and increased γ-aminobutyric acid (GABA) output contributes to counterregulatory failure in recurrently hypoglycemic (RH) and diabetic rats...

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Detalles Bibliográficos
Autores principales: Chan, Owen, Paranjape, Sachin A., Horblitt, Adam, Zhu, Wanling, Sherwin, Robert S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837027/
https://www.ncbi.nlm.nih.gov/pubmed/23939392
http://dx.doi.org/10.2337/db13-0770

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837027/
https://www.ncbi.nlm.nih.gov/pubmed/23939392
http://dx.doi.org/10.2337/db13-0770

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