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Glucose-6-Phosphate–Mediated Activation of Liver Glycogen Synthase Plays a Key Role in Hepatic Glycogen Synthesis

The liver responds to an increase in blood glucose levels in the postprandial state by uptake of glucose and conversion to glycogen. Liver glycogen synthase (GYS2), a key enzyme in glycogen synthesis, is controlled by a complex interplay between the allosteric activator glucose-6-phosphate (G6P) and...

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Detalles Bibliográficos
Autores principales: von Wilamowitz-Moellendorff, Alexander, Hunter, Roger W., García-Rocha, Mar, Kang, Li, López-Soldado, Iliana, Lantier, Louise, Patel, Kashyap, Peggie, Mark W., Martínez-Pons, Carlos, Voss, Martin, Calbó, Joaquim, Cohen, Patricia T.W., Wasserman, David H., Guinovart, Joan J., Sakamoto, Kei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837029/
https://www.ncbi.nlm.nih.gov/pubmed/23990365
http://dx.doi.org/10.2337/db13-0880