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Glucose-6-Phosphate–Mediated Activation of Liver Glycogen Synthase Plays a Key Role in Hepatic Glycogen Synthesis
The liver responds to an increase in blood glucose levels in the postprandial state by uptake of glucose and conversion to glycogen. Liver glycogen synthase (GYS2), a key enzyme in glycogen synthesis, is controlled by a complex interplay between the allosteric activator glucose-6-phosphate (G6P) and...
Autores principales: | von Wilamowitz-Moellendorff, Alexander, Hunter, Roger W., García-Rocha, Mar, Kang, Li, López-Soldado, Iliana, Lantier, Louise, Patel, Kashyap, Peggie, Mark W., Martínez-Pons, Carlos, Voss, Martin, Calbó, Joaquim, Cohen, Patricia T.W., Wasserman, David H., Guinovart, Joan J., Sakamoto, Kei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837029/ https://www.ncbi.nlm.nih.gov/pubmed/23990365 http://dx.doi.org/10.2337/db13-0880 |
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