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Antiangiogenic and Antineuroinflammatory Effects of Kallistatin Through Interactions With the Canonical Wnt Pathway

Kallistatin is a member of the serine proteinase inhibitor superfamily. Kallistatin levels have been shown to be decreased in the vitreous while increased in the circulation of patients with diabetic retinopathy (DR). Overactivation of the Wnt pathway is known to play pathogenic roles in DR. To inve...

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Detalles Bibliográficos
Autores principales: Liu, Xiaochen, Zhang, Bin, McBride, Jeffrey D., Zhou, Kevin, Lee, Kyungwon, Zhou, Yueping, Liu, Zuguo, Ma, Jian-xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837048/
https://www.ncbi.nlm.nih.gov/pubmed/23884893
http://dx.doi.org/10.2337/db12-1710