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STAT4 Deficiency Reduces Obesity-Induced Insulin Resistance and Adipose Tissue Inflammation

Signal transducer and activator of transcription (STAT) 4 is one of the seven members of the STAT family. STAT4 has a prominent role in mediating interleukin-12–induced T-helper cell type 1 lineage differentiation. T cells are key players in the maintenance of adipose tissue (AT) inflammation. The r...

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Detalles Bibliográficos
Autores principales: Dobrian, Anca D., Galkina, Elena V., Ma, Qian, Hatcher, Margaret, Aye, Sabai Myo, Butcher, Mathew J., Ma, Kaiwen, Haynes, Bronson A., Kaplan, Mark H., Nadler, Jerry L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837053/
https://www.ncbi.nlm.nih.gov/pubmed/23939393
http://dx.doi.org/10.2337/db12-1275