On-Line Electrochemical Reduction of Disulfide Bonds: Improved FTICR-CID and -ETD Coverage of Oxytocin and Hepcidin

Particularly in the field of middle- and top-down peptide and protein analysis, disulfide bridges can severely hinder fragmentation and thus impede sequence analysis (coverage). Here we present an on-line/electrochemistry/ESI-FTICR-MS approach, which was applied to the analysis of the primary struct...

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Detalles Bibliográficos
Autores principales: Nicolardi, Simone, Giera, Martin, Kooijman, Pieter, Kraj, Agnieszka, Chervet, Jean-Pierre, Deelder, André M., van der Burgt, Yuri E. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837188/
https://www.ncbi.nlm.nih.gov/pubmed/24018861
http://dx.doi.org/10.1007/s13361-013-0725-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837188/
https://www.ncbi.nlm.nih.gov/pubmed/24018861
http://dx.doi.org/10.1007/s13361-013-0725-7

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