Low BRAF and NRAS expression levels are associated with clinical benefit from DTIC therapy and prognosis in metastatic melanoma

Metastatic melanoma is characterized by a poor response to chemotherapy. Furthermore, there is a lack of established predictive and prognostic markers. In this single institution study, we correlated mutation status and expression levels of BRAF and NRAS to dacarbazine (DTIC) treatment response as w...

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Detalles Bibliográficos
Autores principales: Birkeland, Einar, Busch, Christian, Berge, Elisabet Ognedal, Geisler, Jürgen, Jönsson, Göran, Lillehaug, Johan Richard, Knappskog, Stian, Lønning, Per Eystein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837233/
https://www.ncbi.nlm.nih.gov/pubmed/23673558
http://dx.doi.org/10.1007/s10585-013-9587-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837233/
https://www.ncbi.nlm.nih.gov/pubmed/23673558
http://dx.doi.org/10.1007/s10585-013-9587-4

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