Low BRAF and NRAS expression levels are associated with clinical benefit from DTIC therapy and prognosis in metastatic melanoma

Metastatic melanoma is characterized by a poor response to chemotherapy. Furthermore, there is a lack of established predictive and prognostic markers. In this single institution study, we correlated mutation status and expression levels of BRAF and NRAS to dacarbazine (DTIC) treatment response as w...

Descripción completa

Detalles Bibliográficos
Autores principales: Birkeland, Einar, Busch, Christian, Berge, Elisabet Ognedal, Geisler, Jürgen, Jönsson, Göran, Lillehaug, Johan Richard, Knappskog, Stian, Lønning, Per Eystein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837233/
https://www.ncbi.nlm.nih.gov/pubmed/23673558
http://dx.doi.org/10.1007/s10585-013-9587-4

Ejemplares similares

Ejemplares similares