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Epigenetic Therapy in Human Choriocarcinoma

Because epigenetic alterations are believed to be involved in the repression of tumor suppressor genes and promotion of tumorigenesis in choriocarcinomas, novel compounds endowed with a histone deacetylase (HDAC) inhibitory activity are an attractive therapeutic approach. HDAC inhibitors (HDACIs) we...

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Detalles Bibliográficos
Autores principales: Takai, Noriyuki, Narahara, Hisashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837331/
https://www.ncbi.nlm.nih.gov/pubmed/24281181
http://dx.doi.org/10.3390/cancers2031683