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Aberrant Crypt Foci: The Case for Inclusion as a Biomarker for Colon Cancer

Aberrant crypt foci (ACF) are one of the earliest histopathological manifestations of colon cancer. In this review, we critically present the molecular, cellular, histopathological, and chemopreventive evidence that ACF are relevant biomarkers for colon cancer. The laboratory and clinical evidence a...

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Detalles Bibliográficos
Autores principales: Wargovich, Michael J., Brown, Vondina R., Morris, Jay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837333/
https://www.ncbi.nlm.nih.gov/pubmed/24281183
http://dx.doi.org/10.3390/cancers2031705