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Isolation of a novel basic FGF-binding peptide with potent antiangiogenetic activity

Basic fibroblast growth factor (bFGF), which plays an important role in tumour angiogenesis and progression, provides a potential target for cancer therapy. Here we screened a phage display heptapeptide library with bFGF and identified 11 specific bFGF-binding phage clones. Two of these clones had i...

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Detalles Bibliográficos
Autores principales: Wu, Xiaoping, Yan, Qiuxia, Huang, Yadong, Huang, Huixian, Su, Zhijian, Xiao, Jian, Zeng, Yaoying, Wang, Yi, Nie, Changjun, Yang, Yongguang, Li, Xiaokun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837584/
https://www.ncbi.nlm.nih.gov/pubmed/20414975
http://dx.doi.org/10.1111/j.1582-4934.2008.00506.x