Bacterial intoxication evokes cellular senescence with persistent DNA damage and cytokine signalling

Cytolethal distending toxins (CDTs) are proteins produced and secreted by facultative pathogenic strains of Gram-negative bacteria with potentially genotoxic effects. Mammalian cells exposed to CDTs undergo cell type-dependent cell-cycle arrest or apoptosis; however, the cell fate responses to such...

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Detalles Bibliográficos
Autores principales: Blazkova, Hana, Krejcikova, Katerina, Moudry, Pavel, Frisan, Teresa, Hodny, Zdenek, Bartek, Jiri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837606/
https://www.ncbi.nlm.nih.gov/pubmed/19650831
http://dx.doi.org/10.1111/j.1582-4934.2009.00862.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837606/
https://www.ncbi.nlm.nih.gov/pubmed/19650831
http://dx.doi.org/10.1111/j.1582-4934.2009.00862.x

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