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Bacterial intoxication evokes cellular senescence with persistent DNA damage and cytokine signalling

Cytolethal distending toxins (CDTs) are proteins produced and secreted by facultative pathogenic strains of Gram-negative bacteria with potentially genotoxic effects. Mammalian cells exposed to CDTs undergo cell type-dependent cell-cycle arrest or apoptosis; however, the cell fate responses to such...

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Detalles Bibliográficos
Autores principales:	Blazkova, Hana, Krejcikova, Katerina, Moudry, Pavel, Frisan, Teresa, Hodny, Zdenek, Bartek, Jiri
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2010
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837606/ https://www.ncbi.nlm.nih.gov/pubmed/19650831 http://dx.doi.org/10.1111/j.1582-4934.2009.00862.x

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