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Piliation of Invasive Streptococcus pneumoniae Isolates in the Era before Pneumococcal Conjugate Vaccine Introduction in Malawi

The pneumococcal pilus has been shown to be an important determinant of adhesion and virulence in mouse models of colonization, pneumonia, and bacteremia. A pilus is capable of inducing protective immunity, supporting its inclusion in next-generation pneumococcal protein vaccine formulations. Whethe...

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Detalles Bibliográficos
Autores principales: Kulohoma, Benard W., Gray, Katherine, Kamng'ona, Arox, Cornick, Jennifer, Bentley, Stephen D., Heyderman, Robert S., Everett, Dean B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837777/
https://www.ncbi.nlm.nih.gov/pubmed/24027261
http://dx.doi.org/10.1128/CVI.00403-13