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Mechanisms of microemulsion enhancing the oral bioavailability of puerarin: comparison between oil-in-water and water-in-oil microemulsions using the single-pass intestinal perfusion method and a chylomicron flow blocking approach

The purpose of the present work was to determine the mechanisms by which microemulsions (MEs) enhance the oral bioavailability of puerarin. The in situ perfusion method was used in rats to study the absorption mechanisms of an oil-in-water (O/W) microemulsion (O/W-ME) and a water-in-oil (W/O) microe...

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Detalles Bibliográficos
Autores principales: Tang, Tian-Tian, Hu, Xiong-Bin, Liao, De-Hua, Liu, Xin-Yi, Xiang, Da-Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838017/
https://www.ncbi.nlm.nih.gov/pubmed/24277986
http://dx.doi.org/10.2147/IJN.S51469