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Herpes Simplex Virus 1 Counteracts Tetherin Restriction via Its Virion Host Shutoff Activity

The interferon-inducible membrane protein tetherin (Bst-2, or CD317) is an antiviral factor that inhibits enveloped virus release by cross-linking newly formed virus particles to the producing cell. The majority of viruses that are sensitive to tetherin restriction appear to be those that acquire th...

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Detalles Bibliográficos
Autores principales: Zenner, Helen L., Mauricio, Rui, Banting, George, Crump, Colin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838292/
https://www.ncbi.nlm.nih.gov/pubmed/24067977
http://dx.doi.org/10.1128/JVI.02167-13