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Integrating Structure to Protein-Protein Interaction Networks That Drive Metastasis to Brain and Lung in Breast Cancer

Blocking specific protein interactions can lead to human diseases. Accordingly, protein interactions and the structural knowledge on interacting surfaces of proteins (interfaces) have an important role in predicting the genotype-phenotype relationship. We have built the phenotype specific sub-networ...

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Detalles Bibliográficos
Autores principales: Engin, H. Billur, Guney, Emre, Keskin, Ozlem, Oliva, Baldo, Gursoy, Attila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838352/
https://www.ncbi.nlm.nih.gov/pubmed/24278371
http://dx.doi.org/10.1371/journal.pone.0081035