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RNA-Based Tools for Nuclear Reprogramming and Lineage-Conversion: Towards Clinical Applications
The therapeutic potential of induced pluripotent stem cells (iPSCs) is well established. Safety concerns remain, however, and these have driven considerable efforts aimed at avoiding host genome alteration during the reprogramming process. At present, the tools used to generate human iPSCs include (...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer US
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838600/ https://www.ncbi.nlm.nih.gov/pubmed/23852582 http://dx.doi.org/10.1007/s12265-013-9494-8 |