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Immunohistochemical and ultrastructural features of congenital melanocytic naevus cells support a stem-cell phenotype

Background Multiple congenital melanocytic naevi (CMN) in one individual are caused by somatic mosaicism for NRAS mutations; however, the lineage of the mutated cells remains uncertain. Objectives To test the hypothesis that CMN may be derived from cutaneous stem cells. Methods Sixty-six CMN samples...

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Detalles Bibliográficos
Autores principales: Kinsler, VA, Anderson, G, Latimer, B, Natarajan, D, Healy, E, Moore, GE, Sebire, NJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838625/
https://www.ncbi.nlm.nih.gov/pubmed/23517330
http://dx.doi.org/10.1111/bjd.12323