High Expression and Purification of Amino-Terminal Fragment of Human Amyloid Precursor Protein in Pichia pastoris and Partial Analysis of Its Properties

The cleaved amino-terminal fragment of human amyloid precursor protein (N-APP) binds death receptor 6 (DR6) and triggers a caspase-dependent self-destruction process, which was suggested to contribute to Alzheimer's disease. To investigate the N-APP-DR6-induced degeneration pathway at the molec...

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Detalles Bibliográficos
Autores principales: Li, Wei, Gao, Xiang, Ren, Junle, An, Ting, Liu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838808/
https://www.ncbi.nlm.nih.gov/pubmed/24308007
http://dx.doi.org/10.1155/2013/836429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838808/
https://www.ncbi.nlm.nih.gov/pubmed/24308007
http://dx.doi.org/10.1155/2013/836429

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