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An Excitable Signal Integrator Couples to an Idling Cytoskeletal Oscillator to Drive Cell Migration

It is generally believed that cytoskeletal activities drive random cell migration while signal transduction events initiated by receptors regulate the cytoskeleton to guide cells. However, we find that the cytoskeletal network, involving Scar/Wave, Arp 2/3, and actin binding proteins, is only capabl...

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Detalles Bibliográficos
Autores principales: Huang, Chuan-Hsiang, Tang, Ming, Shi, Changji, Iglesias, Pablo A., Devreotes, Peter N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838899/
https://www.ncbi.nlm.nih.gov/pubmed/24142103
http://dx.doi.org/10.1038/ncb2859