BRCA1 and CtIP suppress long tract gene conversion between sister chromatids

BRCA1 controls early steps of the synthesis-dependent strand annealing (SDSA) pathway of homologous recombination, but has no known role following Rad51-mediated synapsis. Here we show that BRCA1 influences post-synaptic homologous recombination events, controlling the balance between short- (STGC)...

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Detalles Bibliográficos
Autores principales: Chandramouly, Gurushankar, Kwok, Amy, Huang, Bin, Willis, Nicholas A., Xie, Anyong, Scully, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838905/
https://www.ncbi.nlm.nih.gov/pubmed/23994874
http://dx.doi.org/10.1038/ncomms3404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838905/
https://www.ncbi.nlm.nih.gov/pubmed/23994874
http://dx.doi.org/10.1038/ncomms3404

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