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BRCA1 and CtIP suppress long tract gene conversion between sister chromatids
BRCA1 controls early steps of the synthesis-dependent strand annealing (SDSA) pathway of homologous recombination, but has no known role following Rad51-mediated synapsis. Here we show that BRCA1 influences post-synaptic homologous recombination events, controlling the balance between short- (STGC)...
Autores principales: | Chandramouly, Gurushankar, Kwok, Amy, Huang, Bin, Willis, Nicholas A., Xie, Anyong, Scully, Ralph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838905/ https://www.ncbi.nlm.nih.gov/pubmed/23994874 http://dx.doi.org/10.1038/ncomms3404 |
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