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Expression of genes encoding the calcium signalosome in cellular and transgenic models of Huntington's disease

Huntington's disease (HD) is a hereditary neurodegenerative disease caused by the expansion of a polyglutamine stretch in the huntingtin (HTT) protein and characterized by dysregulated calcium homeostasis. We investigated whether these disturbances are correlated with changes in the mRNA level...

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Detalles Bibliográficos
Autores principales: Czeredys, Magdalena, Gruszczynska-Biegala, Joanna, Schacht, Teresa, Methner, Axel, Kuznicki, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838962/
https://www.ncbi.nlm.nih.gov/pubmed/24324398
http://dx.doi.org/10.3389/fnmol.2013.00042